Objective monitoring of cognitive impairment by amyloid image analysis

This project proposes the development of a PET system that incorporates new algorithms of classification that allow the analysis of β-amyloid as a mechanism to analyze the effectiveness of the drugs tested. The following elements will be developed:

• Automatic classification algorithms of PET images, generated by β.-amyloid tracers, applied to Alzheimer’s disease
• CADx (Computer Aided Diagnostic) clinical software, according to the international normative medical device software for IEC 62304, for use by Medical personnel in the automated diagnosis of Alzheimer’s disease.
• Development of a head movement compensation / immobilization system of the patient to facilitate PET image acquisition of the brain.
• Development of new PET image reconstruction algorithms (including compensation of movement if required), adapted to the use of multi-core graphics processors (GPUs)
• Design and development of a brain PET prototype unit.
• Validation of the system.

This project has beed co-financed by the European Union through the European Regional Development Fund (ERDF).
Este proyecto ha sido co-financiado por la Unión Europea a través del Fondo Europeo de Desarrollo Regional (FEDER).