Research
Publications (MIRG)
Peer-reviewed publications:
Artificial Intelligence on FDG PET Images Identifies Mild Cognitive Impairment Patients with Neurodegenerative Disease
J Prats ; M T Gandia; I Torres; L Alvarez; B Martínez; C Cháfer; I Gómez; L Cerdá; F Aparici; M Baquero; MJ Rodríguez-Álvarez; L Martí
J Med Syst 46, 52 (2022). https://doi.org/10.1007/s10916-022-01836-w
Development of a Standing Equine Leg CT (slCT)
L. Moliner, N. Bolas, E. Pallas, M.J. Rodríguez-Álvarez and J.M. Benlloch
JINST 17 C03003(2022). https://doi.org/10.1088/1748-0221/17/03/C03003
Fast Energy Dependent Scatter Correction for List-Mode PET Data
JM Álvarez-Gómez, J Santos, L Moliner, MJ Rodríguez-Álvarez.
J. Imaging 2021, 7(10), 199; https://doi.org/10.3390/jimaging7100199
MR Images, Brain Lesions, and Deep Learning
D Castillo, V Lakshminarayanan, MJ Rodríguez-Álvarez.
Appl. Sci. 2021, 11, 1675. https://doi.org/10.3390/app11041675
MTS image analyzer: a software tool to identify mesial temporal sclerosis in MRI images
D. Castillo, J. Macas, R. Samaniego, Y. Jiménez, M. J. Rodríguez-Álvarez, Vasudevan Lakshminarayanan
Applications of Digital Image Processing XLIV; 1184215 (2021) https://doi.org/10.1117/12.2594199
Event: SPIE Optical Engineering + Applications, 2021, San Diego, California, United States
Simulation Study of a Frame-Based Motion Correction Algorithm for Positron Emission Imaging
H Espinós, D Cascales, M Vergara, A Hernández, JM Benlloch, MJ Rodríguez-Álvarez
Sensors 2021, 21, 2608. https://doi.org/10.3390/s21082608
2D feasibility study of joint reconstruction of attenuation and activity in limited angle TOF-PET
M Vergara, A Rezaei, G Schramm, MJ Rodríguez-Álvarez, JM Benlloch, J Nuyts.
IEEE Trans Radiat Plasma Med Sci. 2021 Sep;5(5):712-722. doi: 10.1109/trpms.2021.3079462.
Assessment of mesial temporal sclerosis through MRI processing
D. Castillo , R. Samaniego, Y. Jiménez, A. Sánchez, J. Carrión, M. J. Rodríguez Álvarez
Proc. SPIE 11469, Emerging Topics in Artificial Intelligence 2020, 114690W (20 August 2020); https://doi.org/10.1117/12.2569043
Deep-Learning-Based Computer- Aided Systems for Breast Cancer Imaging: A Critical Review
Y. Jiménez‐Gaona, M.J.Rodríguez‐Álvarez and V. Lakshminarayanan
Appl. Sci. 2020, 10, 8298; doi:10.3390/app10228298
Simulation Study for Designing a Dedicated Cardiac TOF-PET System
S. Oliver, L. Moliner, V. Ilisie, J.M. Benlloch and M.J.Rodríguez-Álvarez
Sensors 2020, 20, 1311; doi:10.3390/s20051311
NEMA Performance Evaluation of CareMiBrain dedicated brain PET and Comparison with the whole-body and dedicated brain PET systems
L. Moliner, M. J. Rodríguez-Alvarez, J.V. Catret, A. González,V. Ilisie, J.M. Benlloch
Scientific Reports | (2019) 9:15484 | https://doi.org/10.1038/s41598-019-51898-z
TOF studies for dedicated PET with open geometries
L. Moliner, V. Ilisie, A. Gonzalez , S. Oliver, A. Gonzalez, V. Gimenez-Alventosa, G. Cañizares, E. Lamprou, J. Alamo, F. Sanchez, M. J. Rodriguez-Alvarez, J. M. Benlloch
2019 JINST 14 C02006 https://doi.org/10.1088/1748-0221/14/02/C02006
Magnetic resonance brain images algorithm to identify demyelinating and ischemic diseases
D. Castillo, René Samaniego, Y. Jiménez, L. Cuenca, O. Vivanco, M. J. Rodríguez-Álvarez,
Proc. SPIE 10752, Applications of Digital Image Processing XLI, 107521W (17 September 2018); doi:10.1117/12.2322048
QR-Factorization Algorithm for Computed Tomography (CT): Comparison With FDK and Conjugate Gradient (CG) Algorithms
M. J. Rodríguez-Alvarez, F. Sánchez, A. Soriano, L. Moliner, S. Sánchez, J. M. Benlloch
IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 2, no. 5, September 2018
Demyelinating and ischemic brain diseases: detection algorithm through regular magnetic resonance images
D. Castillo, René Samaniego, Y. Jiménez, L. Cuenca, O. Vivanco, M. J. Rodríguez-Álvarez
Proceedings Volume 10396, Applications of Digital Image Processing XL; 103961C (2017) https://doi.org/10.1117/12.2274579
Strategies of statistical windows in PET image reconstruction to improve the user’s real time experience
L. Moliner, C. Correcher, V. Gimenez-Alventosa, V. Ilisie, J. Alvarez, S.Sanchez and M. J. Rodríguez-Alvarez
IOP Conf. Series: Journal of Physics: Conf. Series 931 (2017) 012025 doi:10.1088/1742-6596/931/1/012025
Performance characteristics of the MAMMOCARE PET system based on NEMA standard,
L. Moliner, C. Correcher, D. Hellingman, J. Alamo, V. Carrilero, A. Orero, A.J. González, J.M. Benlloch,
Instrum. 2017 Jan 3;12(1):C01014–C01014
A novel semi-robotized device for high-precision 18 F-FDG-guided breast cancer biopsy,
D. Hellingman, S.C. Teixeira, M.L. Donswijk, E.J. Rijkhorst, L. Moliner, J. Alamo, C.E. Loo, R.A. Valdés Olmos, M.P.M. Stokkel,
Rev Esp Med Nucl Imagen Mol . 2017 May;36(3):158–65.
Biopsy system guided by positron emission tomography in real-time,
L. Moliner, J. Álamo, D. Hellingman, J.L. Peris, J. Gomez, P. Tattersall, V. Carrilero, A. Orero, C. Correcher, J.M. Benlloch, In: Kontos D, Flohr TG, Lo JY, editors. 2016. p. 97832H.
Demyelinating and ischemic brain diseases: detection algorithm through regular magnetic resonance images
D. Castillo, René Samaniego, Y. Jiménez, L. Cuenca, O. Vivanco, M. J. Rodríguez-Álvarez
SPIEDigitalLibrary.org/conference-proceedings-of-spie
Online image corrections applied to a dedicated breast PET,
L. Moliner, A.J. González, C. Correcher, J.M. Benlloch,
J. Instrum. 2016 Mar 16;11(3):C03035–C03035.
A new method for image reconstruction in computed tomography (CT) using QR-Decomposition: Image quality assessment
A. Iborra, M.J. Rodriguez-Alvarez, A. Soriano, F. Sanchez, A. Aguilar, P. Bellido, P. Conde, A.J. Gonzalez, L. Moliner, J.P. Rigla, S. Sanchez, M. Seimetz, J.C. Valderas, J.M. Benlloch,
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). IEEE; 2015. p. 1–4.
Noise Analysis in Computed Tomography (CT) Image Reconstruction using QR-Decomposition Algorithm,
A. Iborra, M.J. Rodriguez-Alvarez, A. Soriano, F. Sanchez, P. Bellido, P. Conde, E. Crespo, A.J. Gonzalez, L. Moliner, J.P. Rigla, M. Seimetz, L.F. Vidal, J.M. Benlloch,
IEEE Trans Nucl Sci . 2015 Jun;62(3):869–75.
Pixel size gradient detector for monolithic crystal PET systems,
L. Moliner, C. Correcher, A.J. Gonzalez, A. Aguilar, P. Bellido, P. Conde, L. Hernandez, A. Iborra, J.P. Rigla, M.J. Rodriguez-Alvarez, F. Sanchez, S. Sanchez, M. Seimetz, A. Soriano, J.M. Benlloch,
2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) . IEEE; 2015. p. 1–4.
Expectation maximization (EM) algorithms using polar symmetries for computed tomography (CT) image reconstruction,
M.J. Rodríguez-Alvarez, A. Soriano, A. Iborra, F. Sánchez, A.J. González, P. Conde, L. Hernández, L. Moliner, A. Orero, L.F. Vidal, J.M. Benlloch,
Comput Biol Med . 2013 Sep;43(8):1053–61.
EM tomographic image reconstruction using polar voxels,
A. Soriano, M.J. Rodríguez-Alvarez, A. Iborra, F. Sánchez, M. Carles, P. Conde, A.J. González, L. Hernández, L. Moliner, A. Orero, L.F. Vidal, J.M. Benlloch,
J. Instrum . 2013 Jan 3;8(1):C01004–C01004.
Effect of noise in CT image reconstruction using QR-Decomposition algorithm,
A. Iborra, M. J. Rodríguez-Alvarez, A. Soriano, F. Sánchez, P. Bellido, P. Conde, E. Crespo, A. J. González, F. Martos, L. Moliner, J. P. Rigla, M. Seimetz, L. F. Vidal and J. M. Benlloch,
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC) . IEEE; 2013. p. 1–4.
Performance evaluation of the dual ring MAMMI breast PET,
A. Soriano, F. Sanchez, V. Carrilero, A. Pardo, L.F. Vidal, C. Vázquez, J. Barberá, M. Seimetz, M.J. Rodríguez-Alvarez, J.P. Rigla, L. Moliner, A. Iborra, L. Hernandez, A.J. González, E. Crespo, P. Conde, P. Bellido, L. Caballero, J.M. Benlloch,
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC). IEEE; 2013. p. 1–4. Available from
Time reconstruction study using tubes of response backprojectors in list mode algorithms, applied to a monolithic crystals based breast PET,
L. Moliner, C. Correcher, A. J. González, P. Conde, E. Crespo, L. Hernández, J.P. Rigla, M. J. Rodríguez-Álvarez, F. Sánchez, A. Soriano, A. Iborra, P. Bellido, M. Seimetz, L. F. Vidal, and J. M. Benlloch,
2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC) . IEEE; 2013. p. 1–5.
Minimization of Parallax Error in Dedicated Breast PET,
A. Soriano, A.J. Gonzalez, F. Sanchez, P. Conde, L. Moliner, A. Orero, M.J. Rodriguez-Alvarez, L.F. Vidal, J.M. Benlloch,
IEEE Trans Nucl Sci . 2013 Apr;60(2):739–45.
Implementation and analysis of list mode algorithm using tubes of response on a dedicated brain and breast PET,
L. Moliner, C. Correcher, A.J. González, P. Conde, L. Hernández, A. Orero, M.J. Rodríguez-Álvarez, F. Sánchez, A. Soriano, L.F. Vidal, J.M. Benlloch,
Nucl InstrumentsMethods Phys Res Sect A Accel Spectrometers, Detect Assoc Equip . 2013 Feb;702:129–32.
Design and evaluation of the MAMMI dedicated breast PET,
L. Moliner, A.J. González, A. Soriano, F. Sánchez, C. Correcher, A. Orero, M. Carles, L.F. Vidal, J. Barberá, L. Caballero, M. Seimetz, C. Vázquez, J.M. Benlloch,
Med Phys . 2012 Aug 15;39(9):5393–404.
Exploiting symmetries for weight matrix design in CT imaging,
M.-J. Rodríguez-Alvarez, F. Sánchez, A. Soriano, A. Iborra, C. Mora,
Math Comput Model . 2011 Oct;54(7–8):1655–64.
Sparse Givens resolution of large system of linear equations: Applications to image reconstruction,
M.-J. Rodríguez-Alvarez, F. Sánchez, A. Soriano, A. Iborra,
Math Comput Model . 2010 Oct;52(7–8):1258–64.
New pixellation scheme for CT algebraic reconstruction to exploit matrix symmetries,
C. Mora, M.J. Rodríguez-Álvarez, J.V. Romero,
Comput Math with Appl . 2008 Aug;56(3):715–26. Available from:
Performance characteristics of the MAMMI PEMT scanner based on NEMA NU 2-2007.
L. Moliner, J.M. Benlloch, M. Carles, C. Correcher, A.J. Gonzalez, A. Orero, F. Sanchez, A. Soriano,
IEEE Nuclear Science Symposuim & Medical Imaging Conference . IEEE; 2010. p. 2591–4.
Performance tests of two portable mini gamma cameras for medical applications,
F. Sánchez, M.M. Fernández, M. Giménez, J.M. Benlloch, M.J. Rodríguez-Alvarez, F. García de Quirós, C.W. Lerche, N. Pavón, J.A. Palazón, J. Martínez, A. Sebastiá,
Med Phys . 2006 Oct 19;33(11):4210–20.
Doctoral Thesis:
Sebastián Sánchez Goez, Nuevos Algoritmos y correcciones en reconstrucción directa de imagen PET, Universitat Politècnica de València
Supervisor : María José Rodríguez Alvarez and Antonio Javier González
Amadeo Iborra Carreres, Development of a new 3D reconstruction algorithm for computed tomography (CT), Universitat Politecnica de Valencia
Supervisors: María José Rodríguez Álvarez and Antonio Soriano Asensi. Año 2015
Monserrat Carles Fariñas, Optimización y caracterización de la calidad de imagen en tomografía por emisión de positrones,University of Valencia
Supervisors: María José Rodríguez Álvarez and Christoph Lerche. Año 2012
María Teresa Mora Mora, Métodos de reconstrucción volumétrica algebraica de imágenes tomográficas. Aplicación a un TAC de pequeños animales y a un simulador TAC. Universitat Politecnica de Valencia
Supervisors: María José Rodríguez Álvarez and Rafael Jacinto Villanueva Micó. Año 2008
On going doctoral thesis
Juan Manuel Álvarez Gómez, Optimización de imagenes PET con geometrías dedicadas, Universitat Politècnica de Valencia
Supervisors: María José Rodríguez Álvarez and Jose Maria Benlloch Baviera
Darwin Patricio Castillo Malla, Processing magnetic resonance images (MRI) algorithm to identify demyelination and ischemia brain lesions, Universitat Politècnica de Valencia
Supervisors: María José Rodríguez Álvarez and Vasudevan Lakshminarayanan
Yuliana Jiménez Gaona, Clasificación de imágenes médicas de mama mediante algoritmos de procesamiento, Universitat Politècnica de Valencia
Supervisors: María José Rodríguez Álvarez and Vasudevan Lakshminarayanan
Master and degree thesis
Santiago Pérez Romero,Segmentación 3D de imágenes médicas de tomografía por emisión de positrones (PET), Universitat Politecnica de Valenica. 14/09/2016.
Supervisor: María José Rodríguez Alvarez.
Javier Ruíz Baragaño, Modelización de la epidemia de la Gripe A (H1N1) mediante redes aleatorias en un entorno de computación distribuida, Universitat Politecnica de Valencia. 28/09/2012.
Supervisor: María José Rodríguez Alvarez and Rafael Jacinto Villanueva Micó.
Amadeo Iborra Carreres, Estudio de simetrías en el diseño de la matriz de pesos para imágenes TAC, Universitat Politecnica de Valencia. 28/06/2011.
Supervisors: María José Rodríguez Alvarez and Rafael Jacinto Villanueva Micó.
Amadeo Iborra Carreres, Reconstrucción de alta resolución en tomografía axial computerizada, Universitat Politecnica de Valencia. 28/09/2010.
Supervisor: María José Rodríguez Alvarez and Rafael Jacinto Villanueva Micó.
José Francisco Pomares Sanz, Cálculo de soluciones analítico numéricas de problemas de difusión mixtos singulares acoplados, Universitat Politecnica de Valencia, 22/06/2000.
Supervisors: María José Rodríguez Alvarez and Rafael Jacinto Villanueva Micó.
José Gisbert Cano, Extractor de datos de RETAIN, Universitat Politecnica de Valencia, 18/02/2000.
Supervisor: María José Rodríguez Alvarez and Rafael Jacinto Villanueva Micó.
José Roman Panicello Wiergo, Autoaprendizaje de inversas generalizadas con Mathematica, Universitat Politecnica de Valencia.14/02/2000.
Supervisor: María José Rodríguez Alvarez and Rafael Jacinto Villanueva Micó.
Ramon Ferrer Olmos, Autoaprendizaje de matrices y determinantes con Mathematica, Universitat Politecnica de Valencia. 14/02/2000.
Supervisors: María José Rodríguez Alvarez and Rafael Jacinto Villanueva Micó.